Normanal 500mg Tablet

Uses of Normanal 500mg Tablet

• Varicose veins
• Hemorrhoids

Side Effects of Normanal 500mg Tablet

Some cases of routine gastric disorders and neurovegetative disorders (feeling of discomfort) have been reported, but discontinuation of treatment is not required in such cases.

How does Normanal 500mg Tablet work?

Normanal 500mg Tablet works by increasing the blood flow in the veins and improving vein function. It also stops the action of chemical substances that cause swelling.

Quick Suggestions:

• It is recommended to avoid the intake of spicy and fried foods as it may help improve your symptoms.
• Normanal 500mg Tablet is prescribed to reduce swelling and restore normal vein function in patients with varicose veins.
• Do not take it for more than three months without medical supervision.
• Inform your doctor if you have any bleeding disorders as this medicine might make bleeding worse.

Indication

• Acute Hemorrhoidal Attacks
• Chronic Hemorrhoidal Disease
• Organic and Functional Chronic Venous Insufficiency of the Lower Limbs with symptoms like heavy legs, pain, and nocturnal cramps.

Pharmacology

• Diosmin and Hesperidin are phlebotomist drugs and vascular-protecting agents.
• They strengthen venous tone by prolonging the activity of noradrenaline in the blood vessel walls.
• This leads to a decrease in venous capacitance, distensibility, and emptying time.
• They protect the microcirculation by fighting against processes that damage it.
• They combat venous inflammation by reducing leukocyte activation and inhibiting the release of inflammatory mediators.
• They normalize capillary permeability and enhance capillary resistance.

Dosage & Administration of Normanal 500mg Tablet

• The dosage varies depending on the condition and the specific product's composition (Diosmin 450 mg & Hesperidin 50 mg or Diosmin 900 mg & Hesperidin 100 mg).
• For conditions like acute hemorrhoidal attacks, chronic hemorrhoids, and chronic venous insufficiency, the recommended dosages and duration are provided.

Interaction

Drug-Drug Interactions:

• Normanal 500mg tablet may interact with several other medications:
  • Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) like diclofenac.
  • Skeletal Muscle Relaxant Drugs such as chlorzoxazone.
  • Antihistamines like fexofenadine.

Drug-Food Interactions:

• It is not advisable to consume alcohol along with Normanal 500mg tablet, as this combination may lead to unpleasant side effects or heightened sensitivity to the effects of alcohol.

Drug-Disease Interactions:

• Before using Normanal 500mg tablet, inform your doctor if you have any of the following conditions:
  • Liver diseases
  • Kidney diseases
  • Heart problems
  • Seizures (fits)
  • Diabetes
  • Allergies to plants or food
  • Bleeding disorders or any other illnesses.

Contraindications

• Do not take Normanal 500mg tablet if you are allergic to any of its ingredients.
• Inform your doctor if you are pregnant, breastfeeding, or have kidney, heart, or liver problems, as your doctor will weigh the benefits against the risks.
• Avoid taking Normanal 500mg Tablet for more than 3 months.

Pregnancy & Lactation

• Experimental studies have not shown teratogenic effects in animals.
• No harmful effects have been reported in humans.
• However, breastfeeding is not recommended during treatment due to a lack of data on excretion into breast milk.

Precautions & Warnings

If hemorrhoidal symptoms persist beyond 15 days, patients are advised to consult a doctor for guidance.

Storage Conditions

• Store in a cool, dry place below 30°C.
• Protect from light and moisture.
• Keep out of the reach of children.